Submitted: 16 Dec 2020
Revision: 26 Dec 2020
Accepted: 27 Dec 2020
ePublished: 28 Dec 2020
EndNote EndNote

(Enw Format - Win & Mac)

BibTeX BibTeX

(Bib Format - Win & Mac)

Bookends Bookends

(Ris Format - Mac only)

EasyBib EasyBib

(Ris Format - Win & Mac)

Medlars Medlars

(Txt Format - Win & Mac)

Mendeley Web Mendeley Web
Mendeley Mendeley

(Ris Format - Win & Mac)

Papers Papers

(Ris Format - Win & Mac)

ProCite ProCite

(Ris Format - Win & Mac)

Reference Manager Reference Manager

(Ris Format - Win only)

Refworks Refworks

(Refworks Format - Win & Mac)

Zotero Zotero

(Ris Format - Firefox Plugin)

Int J Phytocos Nat Ingred. 2020;7(1): 12.
doi: 10.15171/ijpni.2020.12
  Abstract View: 74
  PDF Download: 44

Original Research

Phytocosmetics and Beyond: The Enzyme Inhibitory Activities of Two Rosaceae Plant Extracts and Their Cupper-Nanoflowers

Ufuk Koca-Caliskan 1* ORCID logo, Ceylan Dönmez 2 ORCID logo, Nuraniye Eruygur 3, Fatma Ayaz 3, Cevahir Altinkaynak 4, Merve Türk 5, Nalan Özdemir 5*

1 Department of Pharmacognosy, Faculty of Pharmacy, Gazi University, 06330, Ankara, Turkey
2 Department of Pharmacognosy, Faculty of Pharmacy, İzmir Katip Çelebi University, 35620, İzmir, Turkey 3
3 Department of Pharmacognosy, Faculty of Pharmacy, Selçuk University, 42250, Konya, Turkey
4 Department of Plant and Animal Production, Avanos Vocational School, Nevşehir Hacı Bektaş Veli University, 50500, Nevşehir, Turkey
5 Department of Chemistry, Faculty of Science, Erciyes University, 38039, Kayseri, Turkey
Ufuk Koca-Caliskan,


In this study organic-inorganic hybrid nanoflowers were synthesized using methanolic extracts of the medicinal plants’ Rosa canina L. and Rubus sanctus Schreber together with copper ions (Cu2+). The synthesized plant extract based–inorganic hybrid nanoflowers (PE-ihNFs) of R.canina (Rc-ihNFs) and R.sanctus (Rs-ihNFs) were characterized by Energy-Dispersive X-ray (EDX), Fourier transform infrared spectrometry (FTIR) and Scanning Electron Microscopy (SEM), X-Ray Diffraction (XRD). Also, several enzymes were selected to determine the enzyme inhibitionactivities of the synthesized PE-ihNFs. For the first-time, enzymes (tyrosinase, α-amylase and α-glucosidase, acetyl and butyryl cholinesterase) inhibition activities of the PE-ihNFs and their plain plant extracts were evaluated in vitro assays. Results showed that the PE-ihNFs demonstrated better α-glucosidase & α-amylase enzyme inhibition activity compared to the plain extracts. These initial studies are promising for the synthesis of these hybrid nanoflowers containing plant extracts, which might have commercial applications in the pharmaceutical and dermo-cosmetics industries.
Keywords: hybrid nanoflowers, enzyme inhibitions, plants extract, phytocosmetics
First Name
Last Name
Email Address
Security code

Abstract View: 74

Your browser does not support the canvas element.

PDF Download: 44

Your browser does not support the canvas element.