Submitted: 05 May 2020
Revision: 04 Dec 2020
Accepted: 25 Dec 2020
ePublished: 27 Dec 2020
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Int J Phytocos Nat Ingred. 2020;7(1): 11.
doi: 10.15171/ijpni.2020.11
  Abstract View: 76
  PDF Download: 36

Original Research

The application of the aqueous extract of milona leaves (Cissampelos sympodialis Eichl) in a cosmetic formulation

Melania Lopes Cornélio*, Margareth Fátima Formiga Melo Diniz


In the light of the search for untried natural active ingredients to provide new possibilities and increased benefits with their application in the cosmetic industry, we have introduced the species Cissampelos sympodialis Eichl (Menispermaceae) into the field of cosmetics. Our research was focused on the aqueous extract of milona leaves (Cissampelos sympodialis) and its application in cosmetic formulations. A phytochemical screening confirming the presence of some classes of secondary metabolites such as alkaloids, tannins, flavonoids and saponins had previously been reported in the literature. Due to its medicinal potential, mentioned in the literature, we applied the aqueous extract of Cissampelos sympodialis leaves in the development of cosmetic formulations, in view of its anti-oxidant and anti-inflammatory properties. On this basis, we consider the extract to be a promising active ingredient for skin and hair care. The aim of the present study was therefore to develop a cosmetic formulation (o/w), namely, a facial care cream containing the aqueous extract of milona leaves and to perform the stability study of the formulation.The stability study showed that the formulation presented no change in organoleptic characteristics, nor in physical and chemical parameters. The mean pH value was 4.5 ± 0.2 and the mean viscosity values were 999 ± 0.3 cP, which remained unchanged throughout the study. Microbiological analysis showed no formation of bacteria or fungi in the formulation containing the aqueous extract of Cissampelos sympodialis. We concluded that the cosmetic formulation containing this innovative raw material presents the desired characteristics for a new product. Further research will be necessary to perform clinical tests with volunteers to verify the benefits for the skin and hair.
Keywords: Cissampelos sympodialis Eichl, aqueous extract, cosmetic formulation, facial cream, milona, skin
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