Paco Noriega
2*, María Sola
2, Angelka Barukcic
2, Katic Garcia
1, Edison Osorio
11 Centro de Investigación y valoración de la Biodiversidad, Universidad Politécnica Salesiana
2 Maestría en Ciencias y Tecnologías Cosméticas, Universidad Politécnica Salesiana
Abstract
The present study was aimed at
assessing the dry extracts from Cinchona Pubescens Valh species, as a potential antioxidant raw material for the cosmetics industry . The
phenolic compound concentration in the extract and flavonoids were 30
mg GAE / g Hyp 2 mg / g. The following
flavonoids were identified in the extract: apigenin, quercetin, catechin and kaempherol.
The antioxidant activity was determined by spectrophotometric methods ABTS and DPPH,
expressed as IC50 (50% inhibition of radical oxidation) were: IC50
DPPH 42.00 ± 0.2 ug / ml and 88.00 ± 0.2 IC50 ABTS ug / ml. In cosmetic formulations (gels and creams) evaluated
through photochemiluminescence a significantly increased antioxidant
potential was observed when compared to the base formula; up to 15 times higher concentrations of the
assay, the behaviour was higher when compared to a positive pattern formulated
with dry extract of Camellia sinensis
Keywords: Cinchona pubescens Vahl, antioxidant activity, flavonoids, photochemiluminescence